Mediterr J Rheumatol 2019;30(1):38-43
Venous thromboembolism events among RA patients
Authors Information
1Department of Medicine 'B', 2Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Israel
3Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel
4Department of Quality Measurements and Research, Chief Physician’s Office, Clalit Health Services, Tel Aviv, Israel
5Siaal Research Center for Family Medicine and Primary Care, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
  1. Houri LE, Watad A, Whitby A, Tiosano S, Comaneshter D, Cohen AD, et al. Coexistence of ischemic heart disease and RA patients-A case control study. Autoimmun Rev 2016;15:393-6. [https://doi.org/10.1016/j.autrev.2016.01.006] [PMID: 26808075]
  2. McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med 2011;365:2205-19. [https://doi.org/10.1056/NEJMra1004965] [PMID: 22150039]
  3. Kang Y, Park HJ, Kang MI, Lee HS, Lee SW, Lee SK, et al. Adipokines, inflammation, insulin resistance, and carotid atherosclerosis in patients with rheumatoid arthritis. Arthritis Res Ther 2013 2013;15:R194. [https://doi.org/10.1186/ar4384] [PMID: 24245495] [PMCID: PMC3978659]
  4. Chung CP, Giles JT, Petri M, Szklo M, Post W, Blumenthal RS, et al. Prevalence of traditional modifiable cardiovascular risk factors in patients with rheumatoid arthritis: comparison with control subjects from the multi-ethnic study of atherosclerosis. Semin Arthritis Rheum 2012;41:535-44. [https://doi.org/10.1016/j.semarthrit.2011.07.004] [PMID: 22340996] [PMCID: PMC3538033]
  5. Busso N, Hamilton JA. Extravascular coagulation and the plasminogen activator/plasmin system in rheumatoid arthritis. Arthritis Rheum 2002;46:2268-79. [https://doi.org/10.1002/art.10498] [PMID: 12355473]
  6. Conn DL, McDuffie FC, Kazmier FJ, Schroeter AL, Sun NC. Coagulation abnormalities in rheumatoid disease. Arthritis Rheum 1976;19:1237-43. [PMID: 999734]
  7. van den Oever IA, Sattar N, Nurmohamed MT. Thromboembolic and cardiovascular risk in rheumatoid arthritis: role of the haemostatic system. Ann Rheum Dis 2014;73:954-7. [https://doi.org/10.1136/annrheumdis-2013-204767] [PMID: 24431395]
  8. Yavne Y, Tiosano S, Watad A, Comaneshter D, Cohen AD, Amital H. Investigating the link between ischemic heart disease and Behcet's disease: A cross-sectional analysis. Int J Cardiol 2017;241:41-5. [https://doi.org/10.1016/j.ijcard.2017.02.135] [PMID: 28285799]
  9. Watad A, Tiosano S, Bragazzi NL, Brigo F, Comaneshter D, Cohen AD, et al. Epilepsy among Systemic Lupus Erythematosus Patients: Insights from a Large Database Analysis. Neuroepidemiology 2017;50:1-6. [https://doi.org/10.1159/000485136] [PMID: 29208845]
  10. Watad A, Abu MA, Bracco D, Mahroum N, Comaneshter D, Cohen AD, et al. Association between ischemic heart disease and systemic lupus erythematosus-a large case-control study. Immunol Res 2017;65:459-63. [https://doi.org/10.1007/s12026-016-8884-9] [PMID: 28093682]
  11. Dar L, Tiosano S, Watad A, Bragazzi NL, Zisman D, Comaneshter D, et al. Are obesity and RA interrelated? Int J Clin Pract 2017;Jan;72(1). Epub 2017 Dec 12. [https://doi.org/10.1111/ijcp.13045] [PMID: 29231278]
  12. Corrales A, Parra JA, Gonzalez-Juanatey C, Rueda-Gotor J, Blanco R, Llorca J, et al. Cardiovascular risk stratification in rheumatic diseases: carotid ultrasound is more sensitive than Coronary Artery Calcification Score to detect subclinical atherosclerosis in patients with rheumatoid arthritis. Ann Rheum Dis 2013;72:1764-70. [https://doi.org/10.1136/annrheumdis-2013-203688] [PMID: 23852762]
  13. Ikdahl E, Rollefstad S, Wibetoe G, Olsen IC, Berg IJ, Hisdal J, et al. Predictive Value of Arterial Stiffness and Subclinical Carotid Atherosclerosis for Cardiovascular Disease in Patients with Rheumatoid Arthritis. J Rheumatol 2016;43:1622-30. [https://doi.org/10.3899/jrheum.160053] [PMID: 27307523]
  14. Lee JH, Cho KI, Kim SM. Carotid arterial stiffness in patients with RAassessed by speckle tracking strain imaging: its association with carotid atherosclerosis. Clin Exp Rheumatol 2012;30:720-28. [PMID: 22766304]
  15. Liu JH, Ng MY, Cheung T, Chung HY, Chen Y, Zhen Z, et al. Ten-year progression of coronary artery, carotid artery, and aortic calcification in patients with rheumatoid arthritis. Clin Rheumatol 2017;36:807-16. [https://doi.org/10.1007/s10067-016-3536-y] [PMID: 28127640]
  16. Chung WS, Peng CL, Lin CL, Chang YJ, Chen YF, Chiang JY, et al. Rheumatoid arthritis increases the risk of deep vein thrombosis and pulmonary thromboembolism: a nationwide cohort study. Ann Rheum Dis 2014;73:1774-80. [https://doi.org/10.1136/annrheumdis-2013-203380] [PMID: 23926057]
  17. Ramagopalan SV, Wotton CJ, Handel AE, Yeates D, Goldacre MJ, et al. Risk of venous thromboembolism in people admitted to hospital with selected immune-mediated diseases: record-linkage study. BMC Med 2011;9:1. [https://doi.org/10.1186/1741-7015-9-1]
  18. Zoller B, Li X, Sundquist J, Sundquist K. Autoimmune diseases and venous thromboembolism: a review of the literature. Am J Cardiovasc Dis 2012;2:171-83. [PMID: 22937487] [PMCID: PMC3427982]
  19. Meyer-Olesen CL, Nielsen SF, Nordestgaard BG. Increased rheumatoid factor and deep venous thrombosis: 2 cohort studies of 54628 individuals from the general population. Clin Chem 2015;61:349-93. [https://doi.org/10.1373/clinchem.2014.233296] [PMID: 25278501]
  20. Cohoon KP, Ransom JE, Leibson CL, Ashrani AA, Petterson TM, Long KH, et al. Direct Medical Costs Attributable to Cancer-Associated Venous Thromboembolism: A Population-Based Longitudinal Study. Am J Med 2016;129:1000-25. [https://doi.org/10.1016/j.amjmed.2016.02.030] [PMID: 27012853] [PMCID: PMC4996698]
  21. Bacani AK, Gabriel SE, Crowson CS, Heit JA, Matteson EL, et al. Noncardiac vascular disease in rheumatoid arthritis: increase in venous thromboembolic events? Arthritis Rheum 2012;64:53-61. [https://doi.org/10.1002/art.33322] [PMID: 21905005] [PMCID: PMC3474372]
  22. Matevosyan K, Sarode R. Thrombosis, Microangiopathies, and Inflammation. Semin Thromb Hemost 2015;41:556-62. [https://doi.org/10.1055/s-0035-1556587] [PMID: 26276936]
  23. Samad F, Ruf W. Inflammation, obesity, and thrombosis. Blood 2013;122:3415-22. [https://doi.org/10.1182/blood-2013-05-427708] [PMID: 24092932] [PMCID: PMC3829115]
  24. Vazquez-Garza E, Jerjes-Sanchez C, Navarrete A, Joya-Harrison J, Rodriguez D, et al. Venous thromboembolism: thrombosis, inflammation, and immunothrombosis for clinicians. J Thromb Thrombolysis 2017;44:377-85. [https://doi.org/10.1007/s11239-017-1528-7] [PMID: 28730407]
  25. van den Oever IA, Sattar N, Nurmohamed MT. Thromboembolic and cardiovascular risk in rheumatoid arthritis: role of the haemostatic system. Ann Rheum Dis 2014;;73:954-7. [https://doi.org/10.1136/annrheumdis-2013-204767] [PMID: 24431395]
  26. Cirillo P, Golino P, Calabro P, Calì G, Ragni M, De Rosa S, et al. C-reactive protein induces tissue factor expression and promotes smooth muscle and endothelial cell proliferation. Cardiovasc Res 2005;68:47-55. [https://doi.org/10.1016/j.cardiores.2005.05.010] [PMID: 16023093]
  27. Davi G, Patrono C. Platelet activation and atherothrombosis. N Engl J Med 2007;357:2482-94. [https://doi.org/10.1056/NEJMra071014] [PMID: 18077812]
  28. Kim KW, Kim BM, Moon HW, Lee SH, Kim HR, et al. Role of C-reactive protein in osteoclastogenesis in rheumatoid arthritis. Arthritis Res Ther 2015;17:41. [https://doi.org/10.1186/s13075-015-0563-z] [PMID: 25889630] [PMCID: PMC4372175]
  29. Peters MJ, Nurmohamed MT, van Eijk IC, Verkleij CJ, Marx PF, et al.  Thrombin-activatable fibrinolysis inhibitor and its relation with inflammation in rheumatoid arthritis. Ann Rheum Dis 2009;68:1232-3. [https://doi.org/10.1136/ard.2008.097485] [PMID: 19525410]