Mediterr J Rheumatol 2020;31(3):358-61
A Rare Case with Systemic Lupus Erythematosus Manifested by two Different Neurologic Entities; Guillain Barre Syndrome and Posterior Reversible Encephalopathy Syndrome
Authors Information

1. Department of Rheumatology, 2. Department of Internal Medicine, and 3. Department of Intensive Care Unit, Faculty of Medicine, Pamukkale University, Denizli, Turkey

Firdevs Ulutaş, Veli Çobankara, Uğur Karasu, Ismail Hakkı Akbudak


Systemic lupus erythematosus (SLE) is an immune-mediated, lifelong disease characterized by quite heterogeneous neuropsychiatric manifestations. Herewith, we report the first rare co-incidental case with posterior reversible encephalopathy syndrome (PRES), Guillain Barre Syndrome (GBS), and (SLE). The coexistence of these neurological conditions in SLE patients could lead to delayed diagnosis and treatment due to this rare coalescence and clinical diversity. Currently, there are no specific, diagnostic radiological or laboratory biomarkers for neurological involvement in SLE. Awareness and, early recognition of neuropsychiatric involvements of the disease are important for timely appropriate treatment. Delayed treatment may cause permanent damage, poor prognosis, long term morbidity, and even death.

Article Submitted: 11 Feb 2020; Revised Form: 12 May 2020; Article Accepted: 10 Jul 2020; Available Online: 30 Sep 2020

This work is licensed under a Creative Commons Attribution 4.0 International License. 

©Ulutaş F, Çobankara V, Karasu U, Baser N, Akbudak IH.