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It is impossible to achieve a diagnosis without a comprehensive list of possible diagnostic explanations for a certain symptom or syndrome. Joint complaints are very frequent in general practice, paediatrics, emergency medicine and naturally rheumatology and orthopaedics. The differential diagnosis of joint and surrounding tissue pain and inflammation is impressively challenging. Orthopaedic surgeons and rheumatologists deal with different aspects of this subject, while primary care physicians need to have a wider perspective that includes both orthopaedic and rheumatic disorders. The purpose of this paper is to provide a unified, comprehensive, clear and concise guide to this subject that will include both orthopaedic and rheumatic disorders and may serve the practitioner as basic reference for differential diagnosis. Short dictionary-style definitions would be given for each disorder in order to provide a ‘bird’s-eye view’, rather than an in-depth description of many diseases. Medical students, residents and primary care physicians are the primary target audience, but we believe that even the experienced orthopaedic surgeon or rheumatologist may benefit from a systematic and well-organised method.

Cite this article as: Krasin E, Hemo Y, Doron R. Stop Searching under the Streetlight! A Primer and Practical Guide to the Diagnosis of Joint Pain and Inflammation. Mediterr J Rheumatol 2022;33(3):291-304.

Article Submitted: 16 Sep 2021; Article Accepted: 29 Nov 2021; Available Online: 30 Sep 2022

https://doi.org/10.31138/mjr.33.3.291

This work is licensed under a Creative Commons Attribution 4.0 International License.

©Krasin E, Hemo Y, Doron R.