Mediterr J Rheumatol 2021;32(2):124-33
The Relationship of Lifestyle with Disease Activity among Patients with Systemic Lupus Erythematosus: A Descriptive-Correlational Study
Authors Information

1. Nursing and Midwifery Care Research Centre, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Internal Medicine, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
3. Nursing, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran

Sayadi L, Faezi ST, Hasanpour M, Alahmadi SJ 


Objective: The objective of this study was to evaluate the relationship of lifestyle with disease activity among patients with systemic lupus erythematosus. Methods: This cross-sectional descriptive-correlational study was conducted in 2019 on 209 patients with systemic lupus erythematosus. Data were collected using a demographic and clinical characteristics questionnaire, the Health-Promoting Lifestyle Profile II, and the systemic lupus erythematosus disease activity Index. The data were analysed through the mixed model and the logistic regression analyses. Results: In total, 67.5% of participants had active disease. The mean score of lifestyle was 2.49±0.30 and the lowest and the highest lifestyle dimensional mean scores were respectively related to the physical activity and the health responsibility dimensions (1.55±0.60 and 3.25±0.45). The analysis showed that each one point increase in the mean score of lifestyle was associated with 0.79 point decrease in the odds of disease activity (P = 0.006). Moreover, disease activity had significant positive relationship with body mass index (P = 0.015). Conclusion: Interventions for promoting lifestyle among these patients and improving healthcare providers’ knowledge about Systemic lupus erythematosus and lifestyle modification are recommended to reduce disease activity.

Article Submitted: 4 Oct 2020; Revised Form: 5 Nov 2020; Article Accepted: 15 Dec 2020; Available Online: 30 Jun 2021


This work is licensed under a Creative Commons Attribution 4.0 International License (CC-BY). 

©Sayadi L, Faezi ST, Hasanpour M, Alahmadi SJ.