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Volume 35, Issue 1, March 2024



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Mediterr J Rheumatol 2023;34(4):592-3
Malic Acid for the Treatment of Rheumatic Diseases
Authors Information

1Núcleo de Pesquisa em Doenças Crônicas não Transmissíveis (NUPEN), School of Nutrition from the Federal University of Bahia, Salvador, Bahia, Brazil

2Chaim Sheba Medical Centre, The Zabludowicz Research Centre for Autoimmune Diseases, Israel

3Ariel University, Ariel, Israel

References
  1. Russell IJ, Michalek JE, Flechas JD, Abraham GE. Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study. J Rheumatol 1995 May;22(5):953-8.
  2. Ferreira I, Ortigoza Á, Moore P. Magnesium and malic acid supplement for fibromyalgia. Medwave 2019 May 28;19(4):e7633.
  3. da Silva Marques DN, da Mata AD, Patto JM, Barcelos FA, de Almeida Rato Amaral JP, et al. Effects of gustatory stimulants of salivary secretion on salivary pH and flow in patients with Sjögren's syndrome: a randomized controlled trial. J Oral Pathol Med 2011 Nov;40(10):785-92. 
  4. da Mata ADSP, Amaral JPAR, Thomson WM, Barcelos F, Vaz Patto J, Pereira RMN, et al. Patient-related outcomes in Sjögren syndrome treated with stimulants of salivary secretion: Randomized clinical trial. Oral Dis 2020 Mar;26(2):313-24. 
  5. Liu G, Qiu X, Tan X, Miao R, Tian W, Jing W. Efficacy of a 1% malic acid spray for xerostomia treatment: A systematic review and meta-analysis. Oral Dis 2023 Apr;29(3):862-72.