Loading...
 

Volume 35, Issue 1, March 2024



Sign in to download the Issue in PDF format.

Back to the list
Mediterr J Rheumatol 2022;33(4):437-43
Article Links
Anti-Jo1 Syndrome: Understanding a Rare Cause of Interstitial Lung Disease
Arun Hegde2, Vikas Marwah1, Shrinath V1, Robin Choudhary1, Virendra Malik3
Authors Information
  1. Department of Respiratory Medicine, AICTS, Pune, India
  2. Department of Rheumatology, Command Hospital, Lucknow, India
  3. Department of Radiology, AICTS, Pune, India

 A Hegde, V Marwah, Shrinath V, R Choudhary, V Malik

Keywords: anti-synthetase syndrome, idiopathic inflammatory myositis, anti-Jo1 antibody, interstitial lung disease
References
  1. Lega JC, Fabien N, Reynaud Q, Durieu I, Durupt S, Dutertre M, et al. The clinical phenotype associated with myositis-specific and associated autoantibodies: a meta-analysis revisiting the so-called antisynthetase syndrome. Autoimmun Rev 2014 Sep 1;13(9):883-91.
  2. Watanabe K, Handa T, Tanizawa K, Hosono Y, Taguchi Y, Noma S, et al. Detection of antisynthetase syndrome in patients with idiopathic interstitial pneumonias. Respir  Medicine 2011 Aug 1;105(8):1238-47.
  3. Katzap E, Barilla-LaBarca ML, Marder G. Antisynthetase syndrome. Cur Rheumatol Rep 2011 Jun 1;13(3):175.
  4. Kumar RR, Jha S, Dhooria A, Minz RW, Kumar S, Sharma SK, et al. Anti-Jo-1 Syndrome Often Misdiagnosed as Rheumatoid Arthritis (for Many Years): A Single-Center Experience. J Clin Rheumatol 2019 Dec 28.
  5. Satoh M, Tanaka S, Ceribelli A, Calise SJ, Chan EK. A comprehensive overview on myositis-specific antibodies: new and old biomarkers in idiopathic inflammatory myopathy. Clin Rev Allergy Immunol 2017; 52:1-19.
  6. Connors GR, Christopher Stine L, Oddis CV, Danoff SK. Interstitial lung disease associated with the idiopathic inflammatory myopathies: what progress has been made in the past 35 years. Chest 2010;138(6):1464-74.
  7. Travis WD, Costabel U, Hansell DM, King Jr TE, Lynch DA, Nicholson AG, et al. An official American Thoracic Society/European Respiratory Society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2013 Sep 15;188(6):733-48.
  8. European RS, American Thoracic Society. American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS executive committee, June 2001. Am J Respir Crit Care Med 2002 Jan 15;165(2):277.
  9. Graham BL, Steenbruggen I, Miller MR, Barjaktarevic IZ, Cooper BG, Hall GL, et al. Standardization of spirometry 2019 update. An official American thoracic society and European respiratory society technical statement. Am J Respir Crit Care Med 2019 Oct 15;200(8):e70-88.
  10. Aggarwal AN, Agarwal R, Dhooria S, Prasad KT, Sehgal IS, Muthu V, et al. Joint Indian Chest Society-National College of Chest Physicians (India) guidelines for spirometry. Lung India 2019 Apr;36(Suppl 1):S1.
  11. Cavagna L, Nuno L, Scire CA, Govoni M, Longo FJ, Franceschini F, et al. Clinical spectrum time course in anti Jo-1 positive antisynthetase syndrome: results from an international retrospective multicenter study. Medicine 2015 Aug;94(32).
  12. Huang K, Aggarwal R. Antisynthetase syndrome: A distinct disease spectrum. J Scleroderma Relat Disord 2020 Oct;5(3):178-91.
  13. Watanabe K, Handa T, Tanizawa K, Hosono Y, Taguchi Y, Noma S, Kobashi Y, Kubo T, Aihara K, Chin K, Nagai S. Detection of antisynthetase syndrome in patients with idiopathic interstitial pneumonias. Respir Med 2011 Aug 1;105(8):1238-47.
  14. Marie I, Hachulla E, Cherin P, Dominique S, Hatron PY, Hellot MF, et al. Interstitial lung disease in polymyositis and dermatomyositis. Arthritis Rheum 2002;47:614-22.
  15. Douglas WW, Tazelaar HD, Hartman TE, Hartman RP, Decker PA, Schroeder DR, et al. Polymyositis-dermatomyositis-associated interstitial lung disease. Am J Respir Crit Care Med 2001;164:1182-5.
  16. Rowen AJ, Reichel J. Dermatomyositis with lung involvement, successfully treated with azathioprine. Respiration 1983;44(2):143-6.
  17. Fischer A, Brown KK, Du Bois RM, Frankel SK, Cosgrove GP, Fernandez-Perez ER, et al. Mycophenolate mofetil improves lung function in connective tissue disease-associated interstitial lung disease. J Rheumatol 2013;40(5):640-6.
  18. Bauhammer J, Blank N, Max R, Lorenz HM, Wagner U, Krause D, et al. Rituximab in the treatment of Jo1 antibody-associated antisynthetase syndrome: anti-Ro52 positivity as a marker for severity and treatment response. J Rheumatol 2016;43(8):1566-74.
  19. Allenbach Y, Guiguet M, Rigolet A, Marie I, Hachulla E, Drouot L, et al. Efficacy of rituximab in refractory inflammatory myopathies associated with anti- synthetase auto-antibodies: an open-label, phase II trial. PLoS One 2015;10(11):e0133702.
  20. Andersson H, Sem M, Lund MB, Aaløkken TM, Günther A, Walle-Hansen R, et al. Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease. Rheumatology (Oxford) 2015;54(8):1420-8.
  21. Dasa O, Ruzieh M, Oraibi O. Successful treatment of life-threatening interstitial lung disease secondary to antisynthetase syndrome using rituximab: a case report and review of the literature. Am J Ther 2016;23(2):e639-e645.
  22. Lepri G, Avouac J, Airo P, Anguita Santos F, Bellando-Randone S, et al. Effects of rituximab in connective tissue disorders related interstitial lung disease. Clin Exp Rheumatol 2016; 34(5):181-5.
  23. Nalotto L, Iaccarino L, Zen M, Gatto M, Borella E, Domenighetti M, et al. Rituximab in refractory idiopathic inflammatory myopathies and antisynthetase syndrome: personal experience and review of the literature. Immunol Res 2013;56(2–3):362-70.
  24. Sem M, Molberg O, Lund MB, Gran JT. Rituximab treatment of the anti-synthetase syndrome: a retrospective case series. Rheumatology (Oxford) 2009;48(8):968-71.
  25. Sharp C, McCabe M, Dodds N, Edey A, Mayers L, Adamali H, et al. Rituximab in autoimmune connective tissue disease-associated interstitial lung disease. Rheumatology (Oxford) 2016;55:1318-24.
  26. Unger L, Kampf S, Luthke K, Aringer M. Rituximab therapy in patients with refractory dermatomyositis or polymyositis: differential effects in a real-life population. Rheumatology (Oxford) 2014; 53(9):1630-8.
  27. Yousem SA, Gibson K, Kaminski N, Oddis CV, Ascherman DP. The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome. Mod Pathol 2010 Jun;23(6):874-80.
  28. Marie I, Josse S, Hatron PY, Dominique S, Hachulla E, Janvresse A, et al. Interstitial Lung Disease in Anti–Jo‐1 Patients With Antisynthetase Syndrome. Arthritis Care Res 2013 May;65(5):800-8.
  29. Marco JL, Collins BF. Clinical manifestations and treatment of antisynthetase syndrome. Best Pract Res Clin Rheumatol 2020 Apr 11:101503.
  30. Dalakas MC, Hohlfeld R. Polymyositis and dermatomyositis. Lancet 2003 Sep 20;362(9388):971-82.
  31. Lega JC, Reynaud Q, Belot A, Fabien N, Durieu I, Cottin V. Idiopathic inflammatory myopathies and the lung. Eur Respir Rev 2015 Jun 1;24(136):216-38.
  32. Schmidt WA, Wetzel W, Friedländer R, Lange R, Sörensen HF, Lichey HJ, et al. Clinical and serological aspects of patients with anti-Jo-1 antibodies–an evolving spectrum of disease manifestations. Clin Rheumatol 2000 Aug;19(5):371-7.
  33. Zhang L, Wu G, Gao D, Liu G, Pan L, Ni L, et al. Factors associated with interstitial lung disease in patients with polymyositis and dermatomyositis: a systematic review and meta-analysis. PLoS One 2016 May 12;11(5):e0155381.
  34. Witt LJ, Curran JJ, Strek ME. The diagnosis and treatment of antisynthetase syndrome. Clin Pulm Med 2016 Sep;23(5):218.
  35. Maturu VN, Lakshman A, Bal A, Dhir V, Sharma A, Garg M, et al. Antisynthetase syndrome: an under-recognized cause of interstitial lung disease. Lung India 2016 Jan;33(1):20.
  36. Fischer A, Swigris JJ, du Bois RM, Lynch DA, Downey GP, Cosgrove GP, et al. Anti-synthetase syndrome in ANA and anti-Jo-1 negative patients presenting with idiopathic interstitial pneumonia. Respir Med 2009 Nov 1;103(11):1719-24.
  37. Imbert-Masseau A, Hamidou M, Agard C, Halloun A, Delangle MH, Audrain M, et al. Antisynthetase syndrome. Three cases and a review of the literature. In Ann Med Interne (Paris) 2003 Nov 1;154(7):483-8.