Loading...
 

Volume 35, Issue 1, March 2024



Sign in to download the Issue in PDF format.

Back to the list
Mediterr J Rheumatol 2022;33(4):459-64
Article Links
Severe Thrombocytopenia as the Main Manifestation of Childhood-Onset Systemic Lupus Erythematosus
Cristian Quintana-Ortega1, Agustín Remesal1, Ana Pérez Vigara2, Manuel Parrón-Pajares2, Montserrat Bret2, Rosa Alcobendas1, Sara Murias1
Authors Information
  1. Paediatric Rheumatology Department, La Paz Children's Hospital, Madrid, Spain
  2. Paediatric Radiology Department, La Paz Children's Hospital, Madrid, Spain

C Quintana-Ortega, S Murias, A Remesal, M Parron-Pajares, M Bret

 
Keywords: children, systemic lupus erythematosus, thrombocytopenia, intensive immunosuppression therapy
References
  1. Klein-Gitelman M, Reiff A, Silverman ED. Systemic lupus erythematosus in childhood. Rheum Dis Clin North Am 2002;28(3):561-vii.
  2. Agarwal I, Kumar TS, Ranjini K, Kirubakaran C, Danda D. Clinical features and outcome of systemic lupus erythematosus. Indian Pediatr 2009;46:711-15.
  3. Tucker LB, Menon S, Schaller JG, Isenberg DA. Adult- and childhood-onset systemic lupus erythematosus: a comparison of onset, clinical features, serology, and outcome. Br J Rheumatol 1995;34(9):866-72.
  4. Fayyaz A, Igoe A, Kurien BT, Danda D, James JA, Stafford HA, et al. Haematological manifestations of lupus. Lupus Sci Med 2015;2:e000078.
  5. Keeling DM, Isenberg DA. Haematological manifestations of systemic lupus erythematosus. Blood Rev 1993;7:199-207.
  6. Gokce M, Bilginer Y, Besbas N, Ozaltin F, Cetin M, Gumruk F, Ozen S. Hematological features of pediatric systemic lupus erythematosus: suggesting management strategies in children. Lupus 2012 Jul;21(8):878-84.
  7. Neely J, von Scheven E. Autoimmune haemolytic anaemia and autoimmune thrombocytopenia in childhood-onset systemic lupus erythematosus: updates on pathogenesis and treatment. Curr Opin Rheumatol 2018;30(5):498-505.
  8. Esteves GCX, Gormezano NWS, Pereira OL, Kern D, Silva CA, Pereira RMR, et al. Distinct clinical correlates of immune thrombocytopenic purpura at diagnosis of childhood-onset and adult SLE. Mod Rheumatol 2018;28(4):649-53.
  9. Mina R, Brunner HI. Update on differences between childhood-onset and adult-onset systemic lupus erythematosus. Arthritis Res Ther 2013;15(4):218. Published 2013 Aug 21.
  10. Livingston B, Bonner A, Pope J. Differences in clinical manifestations between childhood-onset lupus and adult-onset lupus: a meta-analysis. Lupus 2011;20:1345-1355.
  11. Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P, et al. Morbidity and mortality in systemic lupus erythematosus during a 5-year period. A multicenter prospective study of 1,000 patients. European Working Party on Systemic Lupus Erythematosus. Medicine (Baltimore) 1999;78: 167-75.
  12. Jallouli M, Frigui M, Marzouk S, Snoussi M, Kechaou M, Kaddour N, et al. Clinical implications and prognostic significance of thrombocytopenia in Tunisian patients with systemic lupus erythematosus. Lupus 2012;21:682-7.
  13. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH. Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum 1992;35:630-40.
  14. Miller MH, Urowitz MB, Gladman DD. The significance of thrombocytopenia in systemic lupus erythematosus. Arthritis Rheum 1983;26:1181-6.
  15. Jung JH, Soh MS, Ahn YH, Um YJ, Jung JY, Suh CH, et al. Thrombocytopenia in Systemic Lupus Erythematosus: Clinical Manifestations, Treatment, and Prognosis in 230 Patients. Medicine (Baltimore) 2016;95(6):e2818.
  16. Parodi A, Davi S, Pringe AB, Pistorio A, Ruperto N, Magni-Manzoni S, et al. Macrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients. Arthritis Rheum 2009;60:3388-99.
  17. Mulliez SM, De Keyser F, Verbist C, Vantilborgh A, Wijns W, Beukinga I, et al. Lupus anticoagulant-hypoprothrombinemia syndrome: report of two cases and review of the literature. Lupus 2015;24(7):736-45.
  18. Tucker LB. Making the diagnosis of systemic lupus erythematosus in children and adolescents. Lupus 2007;16:546-49.
  19. Karpatkin S. Autoimmune thrombocytopenic purpura. Semin Hematol 1985;22:260-88.
  20. Tamaddoni A, Yousefghahari B, Khani A, Esmaeilidooki M, Barari Sawadkouhi R, Mohammadzadeh I. Isolated thrombocytopenia; A report of a rare presentation of childhood systemic lupus erythematosus (SLE). Caspian J Intern Med 2015;6(3):174-6.
  21. Oliveira SKF, Knupp S, Lino K. Outcome of juvenile systemic lupus erythematosus presenting with immune thrombocytopenic purpura: Report of 4 cases. XIV European League Against Rheumatism Congress, Glasgow 6-11 June (Abstract) 1999;362.
  22. Zhao H, Li S, Yang R. Thrombocytopenia in patients with systemic lupus erythematosus: significant in the clinical implication and prognosis. Platelets 2010;21:380-5.
  23. Silverman E, Eddy A. Systemic Lupus Erythematosus. Cassidy JT, Laxer RM, Petty RE, Lindsley CB, editors. Textbook of Pediatric Rheumatology (Sixth Edition), W.B. Saunders, 2011, Pages 315-43.
  24. Hakim AJ, Machin SJ, Isenberg DA. Autoimmune thrombocytopenia in primary antiphospholipid syndrome and systemic lupus erythematosus: the response to splenectomy. Semin Arthritis Rheum 1998;28:20-5.
  25. Zhu FX, Huang JY, Ye Z, Wen QQ, Wei JC. Risk of systemic lupus erythematosus in patients with idiopathic thrombocytopenic purpura: a population-based cohort study. Ann Rheum Dis 2020 Jun;79(6):793-9.
  26. 26.Goulielmos GN, Zervou MI. Risk of systemic lupus erythematosus in patients with idiopathic thrombocytopenic purpura: population-based cohort study. Ann Rheum Dis 2020;annrheumdis-2020-218128.
  27. Costagliola G, Mosca M, Migliorini P, Consolini R. Pediatric Systemic Lupus Erythematosus: Learning From Longer Follow Up to Adulthood. Front Pediatr 2018 May 16;6:144.