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Volume 33, Issue 3, September 2022



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Mediterr J Rheumatol 2022;33(3):316-21
Extra-Articular Manifestations in Patients with Ankylosing Spondylitis: Baseline Characteristics from the RBSMR Study
Authors Information

1Department of Rheumatology, Military Hospital Mohammed V, Ibn Sina University Hospital, Rabat, Morocco

2Laboratory of Biostatistical, Clinical and Epidemiological Research, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco

3Department of Rheumatology, Provincial Hospital of Temara, Morocco

4Department of Rheumatology A, El Ayachi Hospital, Ibn Sina University Hospital, Salé, Morocco

5Department of Rheumatology B, El Ayachi Hospital, Ibn Sina University Hospital, Salé, Morocco

6Department of Rheumatology, Arrazi University Hospital, Marrakech, Morocco

7Department of Rheumatology, University Hospital of Agadir, Morocco

8Department of Rheumatology, Military Hospital Moulay Ismail, Hassan II University Hospital, Meknès, Morocco

9Department of Rheumatology, Hassan II University Hospital, Fès, Morocco

10Department of Rheumatology, Mohammed VI University Hospital, Oujda, Morocco

11Department of Rheumatology, Ibn Rochd University Hospital, Casablanca, Morocco

12Department of Rheumatology, Military Hospital Avicenne, Mohammed VI University Hospital, Marrakech, Morocco

13Private Medical Office, Rabat, Morocco

N El Ouardi

Abstract

Objectives: To describe and analyse the prevalence of extra-articular manifestations (EAMs) including acute anterior uveitis (AAU), psoriasis and inflammatory bowel disease (IBD) in patients with ankylosing spondylitis (AS) in the Moroccan registry of biological therapies in rheumatic diseases RBSMR (Registre des Biothérapies de la Société Marocaine de Rhumatologie). Methods: A cross-sectional, multicentre and analytical study based on the RBSMR database, which included 170 AS. Incidence rates for the development of AAU, psoriasis and IBD were calculated, and risk factors were analysed.

Results: Prevalence of EAMs in AS was 13.5%, 4.7% and 11.2% for AAU, psoriasis and IBD respectively. No significant differences were found while establishing a comparison of the prevalence of these EAMs between AS patients with and without peripheral arthritis. Interestingly, AAU was the most common EAM, and was positively associated in multivariable regression with family history of spondyloarthritis (OR= 7.21, CI 95%: 2.23 -23.24). Conclusions: AAU was the leading EAM in patients with AS included in the Moroccan biotherapy registry (RBSMR) and it was associated with family history of spondyloarthritis.

Cite this article as: El Ouardi N, Djossou HJ, Taoubane L, Ghassem AM, Toufik H, Majjad A, Sadni S, Hmamouchi I, Abouqal R,Bahiri R, Allali F, El Bouchti I, Ghozlani I, Hassikou H, Harzy T, Ichchou L, Mkinsi O, Niamane R, El Maghraoui A, Achemlal L. Extra-Articular Manifestations in Patients with Ankylosing Spondylitis: Baseline Characteristics from the RBSMR Study. Mediterr J Rheumatol 2022;33(3):316-21.

Article Submitted: 2 May 2021; Revised Form: 17 Jul 2021; Article Accepted: 30 Jul 2021; Available Online: 30 Sep 2022

https://doi.org/10.31138/mjr.33.3.316

This work is licensed under a Creative Commons Attribution 4.0 International License.

©El Ouardi N, Djossou HJ, Taoubane L, Ghassem AM, Toufik H, Majjad A, Sadni S, Hmamouchi I, Abouqal R,Bahiri R, Allali F, El Bouchti I, Ghozlani I, Hassikou H, Harzy T, Ichchou L, Mkinsi O, Niamane R, El Maghraoui A, Achemlal L.